| Klinefelter syndrome sometimes called Klinefelter's, KS or XXY is where boys and men are born with an extra X chromosome | The syndrome can affect different stages of physical, language, and social development |
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| French Klinefelter Syndrome The Journal of Clinical Klinefelter syndrome KS has a prevalence of 1:600, and it is the most common sex chromosomal disorder | Google Search- Information is very negative and only talks about health related and educational problems |
| Chromosomes are packages of genes found in every cell in the body• Objective To increase awareness among general practitioners of their role in the diagnosis and management of KS | 1 KS is characterized by X chromosome polysomy with X disomy being the most common variant 47,XXY |
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| g manifest at an early age | In 1959, these men with Klinefelter syndrome were discovered to have an extra X chromosome genotype XXY instead of the usual male sex complement genotype XY Klinefelter syndrome KS is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000 newborn boys Lanfranco et al |
Klinefelter in 1942 Klinefelter, 1942 , and the disorder was subsequently found to be caused by the presence of an extra X chromosome Jacobs and Strong, 1959.
8| Annales d'endocrinologie Paris , 71 6 , 494-504 | Other sex chromosomal aneuploidies have also been described, although they are much less frequent, with 48,XXYY and 48,XXXY |
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| Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development | Boys normally have one X and one Y chro-mosome, but most boys with Klinefelter syndrome have two X and one Y chromosome |
Klinefelter Syndrome 2 About this Book This booklet, Klinefelter Syndrome introduces a genetic condition which affects some boys, and its features from infancy to adulthood.